Advantages of dry granulator

Advantages of dry granulator: In general, dry granulation does not need to add additives, and can directly make dry powder into granules, increase the bulk density, improve the appearance and fluidity, and control the degree of disintegration, which is convenient for storage and transportation. Method granulation saves energy, improves the multiple processes of wet granulation, and reduces pollution. Effective sterilization, in addition, it is more effective for granulating drugs that are unstable under certain humid and hot conditions.

The scope of application of the dry granulator: general materials containing crystal water, Chinese medicine extracts, and materials containing a certain amount of water (about 3-8%) can be granulated by dry method, except for a few special materials such as flour, carbon black, and graphite. Such materials are difficult to granulate, and it is also difficult to granulate pure Chinese medicine without special treatment. You can consider adding appropriate auxiliary materials; the fineness of powder is preferably about 80-300 mesh, coarser or finer Powder has a greater impact on dry powder granulation: for coarser powder, the granulation is not uniform, for finer powder, there are certain difficulties in feeding and tableting, which will directly affect the yield of granules.

Yield rate of dry granulator: The principle of dry granulator is to directly compress the dry powder into flakes and then pulverize and sizing. Therefore, the high and low yield in dry granulation is directly related to the material formula. The yield of materials with good properties should be higher; in addition, it has a great relationship with the strength of the compressed tablets, the structure of the pelletizing cutter and the speed of crushing. The strength of the tablets is related to the size of the pressure and the speed of feeding and pressing. The feeding process is also a pre-pressing process and degassing process. If the air in the material is exhausted as much as possible, and the material has a pre-stay area, so that the pressed piece will not appear intermittent, so that it will remain unchanged in other situations In this case, the yield rate will be relatively increased; the pelletizing tool structure will directly affect the pelletizing rate. If the compressed tablets are pulverized frequently in the pelletizing box, the yield rate will also be reduced. Refer to the foreign pelletizing method using rolling The pressure type makes the material roll out from the screen quickly, which improves the yield. In addition, the slower the crushing speed, the higher the yield of particles, and the slower possible without blocking the mesh. The domestic standard dry granulator meets the requirements as long as the finished product rate reaches 30%. (Taking starch as the standard 20-60 mesh) The problem of discoloration of the material during the granulation process: The color of the general material after dry granulation will be different from the original powder. Because the surface area of the powder is larger than the surface area of the particles, it also reflects the light. The difference is that the packing density of the compressed particles increases compared to the original powder, so the color of the particles will also darken. Generally, the greater the pressure on the pressure wheel, the darker the color will become. The pressure is not only the pressure of the oil pump, but also related to the feeding speed and the tablet pressing speed. When the pressure and the tablet pressing speed are constant, the faster the feeding speed, the greater the pressure acting on the pressure rollers, and vice versa. When the pressure and feeding speed are constant, the slower the tablet pressing speed, the greater the pressure acting between the pressing wheels, and vice versa. Therefore, users should choose a great pressure and speed according to the actual conditions of the material when using the dry granulator, so as to increase the primary yield of the product on the basis of ensuring the product performance.

Dry granulator parameter adjustment problem: Dry granulator is suitable for a variety of materials, so the pressure, feeding, tableting, crushing, and granulating speed of the dry granulator can be adjusted. The requirement will be higher. Generally, the manufacturer will provide a relative parameter before leaving the factory, but in actual use, it should be adjusted reasonably according to the characteristics of the material and the required particle firmness and particle size. Generally, for materials with better fluidity, feed The speed can be slower, and the pressure for easy-forming materials can be lower. For larger particles, the crushing speed can be slower, as long as the screen mesh is not blocked. When adjusting, other parameters can be adjusted. Under the same condition, adjust a parameter appropriately. In short, to adjust the parameters, as long as you grasp the meaning of each parameter, you can adjust it according to the specific situation during actual operation, and it is also by continuous experimentation to summarize experience to achieve great results.

Roundness of dry granulator particles: When comparing the roundness of dry granulation and wet granulation, dry granulation is slightly worse, but the roundness of dry granulation is related to the thickness of the tablet and the form of the granulating tool. A certain relationship, (except for the material itself), the roundness of the particles can be improved by changing the thickness of the sheet. Generally, the thickness of the pressed sheet can be adjusted appropriately according to the particle size, so that the roundness of the particles after the size is better One point, another improvement in the structure of the whole grain knife can also improve the roundness of the grain. In short, before choosing a dry granulator, I hope that the customer can send us some materials and do a test to see if the pellets can meet the needs of the customer, because every material and formula will be different. As a result, so that customers can choose more suitable equipment.